Traduction de «endocrine » (Anglais → Français) :

Examples are the EU legislation on occupational safety and health (where the legislation on chemical agents at work includes all chemical agents, including endocrine disruptors), food and feed safety (where toxicological risks, including those stemming from endocrine disruptors, are subject to comprehensive risk assessment), and consumer products (including for example cosmetics and toys, REACH), as well as environmental legislation.

11. Calls on the Commission to introduce in all relevant EU legislation appropriate testing requirements for the identification of substances with endocrine-disrupting properties; considers that the most recently validated and internationally recognised testing methods – such as those developed by the OECD, the European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) or the US Environmental protection Agency (EPA) Endocrine Disruptor Screening Program – must be implemented; notes that the OECD programme of testing methods covers sex hormones and thyroid hormones as well as steroidogenesis; points out, on the ...[+++] other hand, that there are no tests for many other areas of the endocrine system, e.g. insulin and growth hormones; considers that testing methods and guidance documents should be developed so as to take better account of endocrine disrupters, possible low-dose effects, combination effects and non-monotonic dose-response relationships, in particular with regard to critical windows of exposure during development;

8. Takes the view that the criteria for defining endocrine disrupters should be based on criteria for defining ‘adverse effect’ and ’endocrine mode of action’; the WHO/IPCS definition being the appropriate basis for that purpose; considers that both ‘adverse effect’ and ’endocrine mode of action’ must be examined and weighed up in parallel in a comprehensive assessment; considers that observed effects should be assumed to be harmful if there is scientific data to indicate this; stresses that any possible combination effects, such as mixtures or cocktail effects, should be taken into consideration;

5. Calls, therefore, on the Commission to submit, as soon as possible, proposals for overarching criteria based on the definition of endocrine disrupters prepared by the World Health Organisation’s International Programme on Chemical Safety (WHO/IPCS), together with testing and information requirements for chemicals on the commercial market, and for EU legislation to make clear what is regarded as a substance with endocrine-disrupting properties; advocates considering the introduction of ‘endocrine disrupter’ as a regulatory class, with different categories based on the strength of evidence;

G. whereas international co-operation in this field focuses on two issues: (1) agreement on a list of reference of endocrine disrupters with which to validate individual endocrine disruption tests (2) the design of a screening and testing programme for endocrine disrupters, including the development of new and review of existing test guidelines to detect endocrine disrupters; programmes to address both human and wildlife effects,

– I think anyone listening to this debate who has never heard of endocrine disrupters would be forgiven for thinking that endocrine disrupters were more to do with some science fiction horror story than their own public health.