Traduction de «synthèse non programmée de l'adn » (Français → Anglais) :

9. These rodent in vivo gene mutation tests are especially relevant to assessing mutagenic hazard in that the assays' responses are dependent upon in vivo metabolism, pharmacokinetics, DNA repair processes, and translesion DNA synthesis, although these may vary among species, among tissues and among the types of DNA damage.

The low numbers of ova available for analysis, even after super-ovulation, and the fact that there is no DNA synthesis in the oocyte, preclude the determination of mutation in female germ cells using transgenic assays (31).

Protocols should be in line with OECD Guideline 471 (Salmonella typhimurium Reverse Mutation Test), 472 (Escherichia coli Reverse Mutation Test), 473 (in vitro Mammalian Chromosomal Aberration Test), 474 (Mammalian Erythrocyte Micronucleus Test), 475 (Mammalian Bone Marrow Chromosomal Aberration Test), 476 (in vitro Mammalian Cell Gene Mutation Test) or 482 (Unscheduled DNA Synthesis in Mammalian Cells in vitro), as well as other relevant OECD Guidelines for in vitro and in vivo assays.

DNA (the coding): genomics, pharmaco-genetics, gene probes, DNA sequencing/synthesis/amplification, and genetic engineering.

The Cologne Council had the bright idea of thinking up a bone to keep the dog busy, the dog in question being the European Parliament, and so it invented this Charter, and Parliament, as it is increasingly accustomed to doing, threw itself upon the proffered bone and gave it a good chew, to such an extent that we are, today, completely under the illusion that we are taking part in some historic event. Yet the real issues before us are the blank pages of the French Presidency’s executive summary, the issue of the Commission and the issue of the weighting of votes within the Council, and Parliament, which has always adopted a strong line w ...[+++]ith the weak and a weak attitude towards the strong and which is going increasingly downhill in its way of approaching matters, can find nothing to say about this planned destruction of the Commission.

The Cologne Council had the bright idea of thinking up a bone to keep the dog busy, the dog in question being the European Parliament, and so it invented this Charter, and Parliament, as it is increasingly accustomed to doing, threw itself upon the proffered bone and gave it a good chew, to such an extent that we are, today, completely under the illusion that we are taking part in some historic event. Yet the real issues before us are the blank pages of the French Presidency’s executive summary, the issue of the Commission and the issue of the weighting of votes within the Council, and Parliament, which has always adopted a strong line w ...[+++]ith the weak and a weak attitude towards the strong and which is going increasingly downhill in its way of approaching matters, can find nothing to say about this planned destruction of the Commission.