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5-alpha reductase
Aldehyde reductase
Aldose reductase
Choose appropiate test of genetic testing
Choose type of genetic testing
Consider type of genetic testing
Decide on type of genetic testing
Fermentation reductase test
Field percolating test
Field percolation test
Field permeability test
HMG CoA reductase
HMG CoA-reductase inhibitor
In-place percolating test
In-place percolation test
In-place permeability test
In-situ percolating test
In-situ percolation test
In-situ permeability test
Oxido-reductase
Oxidoreductase
Reductase test
Ribonucleotide reductase
Statin
ß-hydroxy-ß-methyl-glutaryl-coenzyme A reductase

Translation of "Reductase test " (English → French) :

TERMINOLOGY
see also In-Context Translations below


fermentation reductase test

épreuve de la réductase et de la lactofermentation


aldose reductase | aldehyde reductase

aldose réductase


HMG CoA reductase | ß-hydroxy-ß-methyl-glutaryl-coenzyme A reductase

HMG-CoA réductase | ß-Hydroxi-ß-methyl-glutaryl-CoA-Reduktase | ß-hydroxy-ß-méthyl-glutaryl-CoA réductase




statin [ HMG CoA-reductase inhibitor ]

statine [ inhibiteur de la HMG-CoA reductase ]






in-situ percolation test [ in-place percolation test | field percolation test | in-situ percolating test | in-place percolating test | field percolating test | in-situ permeability test | in-place permeability test | field permeability test ]

mesure en place du coefficient de perméabilité [ essai de perméabilité in-situ | essai de perméabilité du sol in-situ ]


choose appropiate test of genetic testing | choose type of genetic testing | consider type of genetic testing | decide on type of genetic testing

décider du type de dépistage génétique
IN-CONTEXT TRANSLATIONS
OECD (2008). Report of the OECD Validation of the Rat Hershberger Bioassay: Phase 2: Testing of Androgen Agonists, Androgen Antagonists and a 5a-Reductase Inhibitor in Dose Response Studies by Multiple Laboratories. Environmental Health and Safety, Monograph Series on Testing and Assessment No 86. ENV/JM/MONO(2008)3.

OCDE (2008), Report of the OECD Validation of the Rat Hershberger Bioassay: Phase 2: Testing of Androgen Agonists, Androgen Antagonists and a 5a-Reductase Inhibitor in Dose Response Studies by Multiple Laboratories, Environmental Health and Safety, Monograph, Series on Testing and Assessment, No. 86, ENV/JM/MONO(2008)3.


Biological activity consistent with androgen antagonists and 5α-reductase inhibitors is tested by administering a reference dose of TP and administering the test chemical for 10 consecutive days.

L'activité biologique correspondant aux antagonistes d'androgènes et aux inhibiteurs de 5α-réductase est analysée par administration d'une dose de référence de TP et administration de la substance d'essai pendant 10 jours consécutifs.


The mode of action characteristics of a test chemical can lead to different relative responses amongst the tissues, for example 5 alpha α-reductase inhibitors, like finasteride, have more pronounced effects on the ventral prostate than other tissues as compared to potent AR antagonists, like flutamide.

Les caractéristiques du mode d'action d'une substance d'essai peuvent aboutir à des réponses relatives différentes entre les tissus, par exemple les inhibiteurs de 5α-réductase, comme le finastéride, exercent des effets plus prononcés sur la prostate ventrale que sur d'autres tissus par rapport à des antagonistes de RA puissants, comme le flutamide.


44. For the test for androgen antagonists and 5α-reductase inhibitors, the TP-treated group is the negative control, and the group coadministered with reference doses of TP and FT is the positive control.

44. En ce qui concerne les essais d'antagonistes d'androgènes et d'inhibiteurs de 5α-réductase, le groupe traité par TP joue le rôle de témoin négatif et le groupe recevant des doses de référence de TP et de FT coadministrées celui de témoin positif.


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3. The Hershberger bioassay serves as a mechanistic in vivo screening assay for androgen agonists, androgen antagonists and 5a-reductase inhibitors and its application should be seen in the context of the “OECD Conceptual Framework for the Testing and Assessment of Endocrine Disrupting Chemicals” (Appendix 2).

3. Le bioessai de Hershberger est utilisé comme un test de dépistage mécanistique in vivo des agonistes d'androgènes, des antagonistes d'androgènes et des inhibiteurs de 5α-réductase, et son application est envisagée dans le contexte du “Cadre conceptuel de l'OCDE pour les essais et l'évaluation des perturbateurs endocriniens” (appendice 2).


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