Traduction de «dose-response assessment » (Anglais → Français) :

dose/response evaluation | dose-response assessment

assess responses to radiation | judge radiation response | analyse radiation response | assess radiation response

dose response assessment

Response Assessment

Client, Acquiring & Analysing, Partnerships, Response, Assessment

dosage related response | dose response | dose-effect relationship | dose-related response | dose-response relationship

evaluate writing in response to feedback | evaluating writings in response to feedback | assess writings in response to feedback | evaluate writings in response to feedback

A Wernicke-like encephalopathy with characteristics of seizures responsive to high doses of thiamine. Two cases have been described so far. Clinical features include epilepsy, nystagmus, ophthalmoplegia and ataxia. The disease results from mutations

Definition: This block contains a wide variety of disorders that differ in severity and clinical form but that are all attributable to the use of one or more psychoactive substances, which may or may not have been medically prescribed. The third character of the code identifies the substance involved, and the fourth character specifies the clinical state. The codes should be used, as required, for each substance specified, but it should be noted that not all fourth character codes are applicable to all substances. Identification of the psychoactive substance should be based on as many sources of information as possible. These include self-report data, analysis of blood and other body fluids, characteristic physical and psychological symptom ...[+++]s, clinical signs and behaviour, and other evidence such as a drug being in the patient's possession or reports from informed third parties. Many drug users take more than one type of psychoactive substance. The main diagnosis should be classified, whenever possible, according to the substance or class of substances that has caused or contributed most to the presenting clinical syndrome. Other diagnoses should be coded when other psychoactive substances have been taken in intoxicating amounts (common fourth character .0) or to the extent of causing harm (common fourth character .1), dependence (common fourth character .2) or other disorders (common fourth character .3-.9). Only in cases in which patterns of psychoactive substance-taking are chaotic and indiscriminate, or in which the contributions of different psychoactive substances are inextricably mixed, should the diagnosis of disorders resulting from multiple drug use (F19.-) be used. | Modifiers The following fourth-character subdivisions are for use with categories F10-F19: Code Title .0 Acute intoxication A condition that follows the administration of a psychoactive substance resulting in disturbances in level of consciousness, cognition, perception, affect or behaviour, o ...

It is therefore important that, in parallel with technological development, appropriate RD is undertaken to provide quantitative data on toxicology and ecotoxicology (including human and environmental dose response and exposure data) to perform risk assessments and, where necessary, to enable risk assessment procedures to be adjusted.

I don't think there's any question about it. On the other hand, if you asked for a risk assessment of X-ray exposure, it would not include the dose to the fetus, because in order to do a dose response for such a problem, it would have to be different for different periods, especially in the first trimester.

The problem is that the whole risk assessment framework is constructed around assumptions about dose response such that the impact of a substance will be a function of the degree to which one is exposed to it.

In a risk assessment, you're limiting your information to research that has been developed to the point that it has a dose response.